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Statins warning: The 90p drink that interacts with drug to make it ‘toxic’ – what to avoid


Statins are a group of medicines that can help lower the level of low-density lipoprotein (LDL) cholesterol in the blood. LDL cholesterol is a waxy substance that clings to your arteries and restricts the flow of blood to vital organs. Over time, this process can increase your risk of heart disease. Statins are therefore a welcome intervention.

“Grapefruit juice contains compounds called furanocoumarins that stop CYP3A from doing its job. As a result, more of the drug is absorbed, making it more powerful than it’s meant to be — even toxic in some cases.”


According to the health body, not all statins are affected equally by grapefruit juice, so grapefruit fans might want to switch to a statin that’s less affected.

The statins that have a potent effect include:

  • Atorvastatin (Lipitor)
  • Lovastatin (Mevacor)
  • Simvastatin (Zocor).

“It’s very important to read the information leaflet that comes with your medicine to check if there are any interactions you should be aware of,” advises the NHS.


“If in doubt, contact a GP or pharmacist for advice.”

It is worth noting that many people who take statins experience no or very few side effects.

The risks of any side effects also have to be balanced against the benefits of preventing serious problems.

A review of scientific studies into the effectiveness of statins found around 1 in every 50 people who take the medicine for five years will avoid a serious event, such as a heart attack or stroke, as a result.

Natural ways to lower high cholesterol

High cholesterol levels can also be lowered by improving aspects of your lifestyle, namely diet and exercise.


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